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Literature summary for 3.5.1.97 extracted from

  • Utari, P.; Setroikromo, R.; Melgert, B.; Quax, W.
    PvdQ quorum quenching acylase attenuates Pseudomonas aeruginosa virulence in a mouse model of pulmonary infection (2018), Front. Cell. Infect. Microbiol., 8, 119 .
    View publication on PubMedView publication on EuropePMC
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Application

Application Comment Organism
drug development therapeutic efficacy of PvdQ acylase as a quorum quenching agent during Pseudomonas aeruginosa infection (mouse model of pulmonary Pseudomonas aeruginosa infection) Pseudomonas aeruginosa
medicine therapeutic efficacy of PvdQ acylase as a quorum quenching agent during Pseudomonas aeruginosa infection (mouse model of pulmonary Pseudomonas aeruginosa infection) Pseudomonas aeruginosa
pharmacology therapeutic efficacy of PvdQ acylase as a quorum quenching agent during Pseudomonas aeruginosa infection (mouse model of pulmonary Pseudomonas aeruginosa infection) Pseudomonas aeruginosa

Organism

Organism UniProt Comment Textmining
Pseudomonas aeruginosa Q9I194
-
-
Pseudomonas aeruginosa DSM 22644 Q9I194
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Pseudomonas aeruginosa

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
N-3-oxododecanoyl-L-homoserine lactone + H2O
-
 Pseudomonas aeruginosa L-homoserine lactone + 3-oxododecanoic acid
-
 ?
N-3-oxododecanoyl-L-homoserine lactone + H2O
-
 Pseudomonas aeruginosa DSM 22644 L-homoserine lactone + 3-oxododecanoic acid
-
 ?

Synonyms

Synonyms Comment Organism
PvdQ acylase
-
 Pseudomonas aeruginosa